Invasive squamous cell carcinoma of the hand in a patient with Kindler syndrome: Case report and literature review, Pulsus Group Inc
PLASTIC SURGERY
The Canadian Society of Plastic Surgeons (CSPS) The Canadian Society for Aesthetic (Cosmetic) Plastic Surgery (CSAPS) Groupe pour L'advancement de la Microchirurgie Canada (GAM) Canadian Society for Surgery of the Hand (Manus Canada)

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Case Reports (Online only) Autumn 2010, Volume 18 Issue 3: e 41-e 43
 

Invasive squamous cell carcinoma of the hand in a patient with Kindler syndrome: Case report and literature review

E Cardin-Langlois | D Hanna | M St-Amant | F Croteau

Kindler syndrome is a rare, autosomal, recessive genodermatosis characterized by trauma-induced acral blisters in infancy and childhood, photosensitivity and progressive poikiloderma. Very few cases in the literature report an association with squamous cell carcinoma, even though it is a very well-known, long-term complication. A case involving a 23-year-old woman with a history of Kindler syndrome who was admitted to the department of plastic surgery (Sherbrooke University, Sherbrooke, Quebec) with an extensive ulcerated squamous cell carcinoma of the right hand is presented. A local excision of the tumour was initially performed, but positive margins and clinically palpable axillary lymphadenopathy over the course of hospitalization necessitated below-elbow amputation and lymph node dissection. To the authors’ knowledge, this is the second reported case of aggressive metastatic squamous cell carcinoma of the hand in a patient with Kindler syndrome.

Aggressive squamous cell carcinoma | Bullous epidermolysis | Kindler syndrome | Photosensitivity | Poikilodermia
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