NSAID-induced small bowel diaphragms and strictures diagnosed with intraoperative enteroscopy
DA Shumaker, K Bladen, RM Katon
Nonsteroidal anti-inflammatory drugs are known to cause
mucosal damage in the stomach and duodenum, which may
lead to hemorrhage and perforation. However, these medications
may also cause damage in the more distal small bowel.
Due to the location of these lesions, currently available
diagnostic testing may yield false negative results.
Two cases of nonsteroidal anti-inflammatory drug-induced
small bowel diaphragms presenting as obscure gastrointestinal
hemorrhage and recurrent small bowel obstruction, respectively,
are discussed. Intraoperative enteroscopy was used to
confirm this diagnosis after other diagnostic tests
failed to identify the etiology. This procedure may
increase the accuracy of exploratory laparotomy in these