Primary chemoradiation as definitive treatment for unresectable cancer of the trachea
GMM Videtic, C Campbell, MD Vincent
64-year-old man was diagnosed with unresectable cancer
of the trachea. He was treated definitively with a novel
chemoradiation regimen. Cisplatin-based chemotherapy
(ChT) was given for two cycles as induction, followed
by concurrent administration of this ChT with external
beam radiotherapy (RT) (total dose 60 Gy). An unexpected
partial tumour response was noted after the induction
of ChT alone. Six weeks after finishing ChT/RT, complete
response of the lesion was noted on computed tomography
imaging. Two years later, the patient was free of disease.
Primary chemoradiation appears to be effective in managing
locally advanced tracheal cancer.