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Volume 3 Journal of Nursing Research and Practice Nursing and Heart 2019
April 22-23, 2019
Nursing Education and Evidence Based Practice Conference
Heart Conference
April 22-23, 2019 Dubai, UAE
World
4th International
&
Coronary computed tomography angiography in coronary artery disease: From diagnosis to prevention
Zhonghua Sun
Curtin University, Australia
Statement of the Problem: Coronary Computed Tomography Angiography (CCTA) has been increasingly used as a less invasive
modality in the diagnosis of coronary artery disease. With rapid technological advances in CT scanning techniques, clinical
applications of CCTA in coronary artery disease have shifted from the traditional visualization of coronary lumen stenosis to
physiological assessments of functional significance of coronary plaques and plaque features. This allows for identification of high-
risk plaques or high-risk patients for developing adverse cardiac events.
Methodology: This presentation provides an overview of clinical value of cardiac CT in coronary artery disease with a focus on five
stages of cardiac CT applications ranging from angiographic evaluation to physiological assessment of coronary plaques.
Findings: CCTA applications are presented to demonstrate the quantitative assessment of coronary plaques in terms of plaque
features, such as calcified, non-calcified and mixed plaques with the aim of identifying high-risk plaques. CCTA is also able to provide
functional assessment of myocardial ischemic changes, thus predicting cardiac events. Furthermore, CCTA-derived Fractional
Flow Reserve (FFRCT) allows for detection of lesion-specific ischemia, with high accuracy than CCTA alone. Latest developments
including 3D printing and artificial intelligence further advance the diagnostic value of CCTA in coronary artery disease.
Conclusion and Significance: CCTA has played an important role in the diagnostic assessment of coronary artery disease due to
its reliability and high diagnostic value. It presents challenges to invasive coronary angiography due to its less invasiveness but with
similar diagnostic accuracy or even better plaque characterization. Current evidence indicates that CCTA has revolutionized patient
screening and management.
Biography
Zhonghua Sun is a Professor and Head of Discipline of Medical Radiation Sciences at Curtin University, Australia. His research interests include diagnostic imaging,
3D medical image visualization and processing (in particular cardiovascular CT imaging), haemodynamic analysis of cardiovascular disease and 3D printing in
cardiovascular disease, and 3D printing in medicine. He has published 3 books, 13 book chapters, and over 240 refereed journal papers in medical/medical imaging
journals. He is a Fellow of the Society of Cardiovascular Computed Tomography. He serves as an associate editor/academic editor for 6 journals and editorial board
member for more than 30 international imaging/medical journals. Specifically, his research on 3D virtual intravascular endoscopy of aortic stent grafts and coronary
plaque features has led to many publications in internationally refereed radiology and surgery journals with high citations, and his recent research on 3D printing in
cardiovascular disease has also produced a number of publications.
Zhonghua Sun, J Nursing Research and Practice, Volume 3
DOI: 10.4172/2632-251X-C3-008