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Volume 02
Stem Cells 2019 & Pediatrics Congress 2019
November 06-07, 2019
Journal of Clinical Genetics and Genomics
November 06-07, 2019 | Tokyo, Japan
STEM CELLS AND REGENERATIVE MEDICINE
PEDIATRICS AND CHILD CARE
International Conference on
2
nd
World Congress on
&
J Clin Gen Genomics, Volume 02
Small mobile stem cells produce strong angiogenic factors leading to tissue remodeling
into macro vessels
Abdulkader Rahmo
SMSbiotech, USA
C
urrent
in vitro
angiogenesis assays capture only early stages of micro- vessel formation. Human derived small mobile stem
(SMS) cells produce matricellular proteins that induce human endothelial cells to form micro and macro vessels. SMS cell
derived extracellular matrix is able, in the absence of any other cell type, to effect human primary endothelial cells microscopic
differentiation and macroscopic tissue organization. This allows the
in vitro
capturing and monitoring of complex multi-stage,
multi-step processes of developing micro vessels into macro-vessels. Notably, the cell differentiation and tissue organization
create stable large vessels that become visible to the naked eye. This capability would provide, first-time, ample opportunities for
interrogating pro or anti- angiogenesis factors,
in vitro
, at significantly more mature stages of vessel formation.
a.rahmo@gmail.com