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Journal of Neurology and Clinical Neuroscience | Volume: 03
8
th
International Conference on
NEUROLOGICAL DISORDERS,
CENTRAL NERVOUS SYSTEM AND STROKE
&
International Conference on
NEUROLOGY AND NEUROSURGERY
December 04-05, Dubai, UAE
Joint event on
J Neurol Clin Neurosci, Volume: 03
Mat r Sci Nanot chnol
Post-operative outcomes after Neurosurgery for Brain tumour excision: A single-
centre service evaluation
Mohini Panikkar
University of Birmingham Medical Society, United Kingdom
Introduction
: Each year, approximately 4400 patients in the
UK are newly diagnosed with a brain tumour.(1,2)The most
commonly presenting tumours are gliomas, meningiomas
and metastases.(2) Post-operative infection rates range
from 2-4% with some patients requiring surgical washouts
and re-do surgeries to address complications.(2) Variables
such as previous radiotherapy and chemotherapy have
been shown to significantly increase post-operative
infection rates after craniotomies in similar patient groups
however limited data exists on the effect of diabetes and
adjunctive immunosuppression.(3,4)
Aims
: The primary aim of this service evaluation is to
investigate the effectiveness of brain tumour excision
surgeries performed at the Queen Elizabeth Hospital by
assessment of post-operative outcomes. In doing this we
also hope to identify risk factors for poor outcomes to
develop quality initiatives to improve (clinical outcomes
and patient experience) in this service.
Methods
: A retrospective analysis of 333 patients who
had undergone neurosurgery for brain tumour excision
was conducted to assess rates of post-operative infection,
wound washouts, redo surgeries and mortality rates. Risk
factors such as diabetes, pre-operative chemotherapy,
radiotherapy and immunosuppression were also assessed
to identify a specific cohort of patients who were most
vulnerable to poor post-operative outcomes.
Results
: The infection rate at the Queen Elizabeth Hospital
was 4%, which is the upper limit of the national average (2-
4%), demonstrating adequate infection control measures
and the mortality rate was marginally lower at 2.4%
(National average is 3%.) An isolated ‘at-risk’ group of
patients was also identified: Immunosuppressed patients
undergoing Glioblastoma resection.
e:
mohinipanikkar@gmail.com