Bacterial infections following pediatric liver transplants

The only curative treatment for both acute and chronic end-stage liver disease in children is Liver Transplantation (LT). However, one of the major reasons of mortality after transplantation is bacterial infection, which calls for attention and the right antibacterial care. In order to provide a comprehensive review of bacterial infections over the course of a year in the largest pediatric LT center in Iran, this study was created.

Patients with end-stage disease and organ failure now enjoy longer life expectancies thanks to advances in medical research. This includes patients who have liver failure. Liver transplantation (LT) is one of the best therapy options for prolonging the lives of patients with advanced liver disease, particularly in kids. Cholestatic conditions, metabolic issues, acute liver failure brought on by viral infections or drug use, chronic hepatitis, and cancers are the most common reasons for LT in children. Even more so than transplant rejection, infections are now one of the leading causes of morbidity and mortality following solid organ transplants. According to various research, pediatric patients experience infections following liver transplants at a rate ranging from 21 to 47%.