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Malignant obstruction of the bile pipe from cholangiocarcinoma, pancreatic adenocarcinoma, or different tumors is a typical issue which may cause weakening side effects and increment the danger of resulting medical procedure. The ideal treatment - including the choice whether to treat preceding resection - relies upon the sort of harm, just as the phase of sickness. Preoperative biliary seepage is commonly debilitated because of the danger of irresistible difficulties, however a few circumstances may profit. Patients who require neoadjuvant treatment will require decompression for the drawn out period until endeavored careful fix. For pancreatic malignant growth patients, self-extending metallic stents are better than plastic stents for accomplishing enduring decompression without stent impediment. For cholangiocarcinoma patients, treatment with percutaneous strategies or nasobiliary waste might be better than endoscopic stent arrangement, with less danger of irresistible intricacies or disappointment. For patients of either harm who have propelled malady with palliative objectives just, the decision of stent for endoscopic decompression relies upon assessed endurance, with plastic stents supported for endurance of < 4 mo. New endoscopic procedures may really broaden stent patency and patient endurance for these patients by accomplishing nearby control of the impeding tumor. Both photodynamic treatment and radiofrequency removal may assume a job in broadening endurance of patients with dangerous biliary check.