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Biomedical Engineering: Current Research

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Herpes reactivation after the injection of hyaluronic acid: case report and literature review

Author(s): Chenyu Wang

Introduction: Hyaluronic acid injections is relatively safe with little risk of complications. Although herpes reactivation after the injection of hyaluronic acid is rare, it produces quite a huge pressure and panic on patients. Quite a lot cosmetic practitioners have no awareness of preventing, diagnosing, and giving correct treatment in time due to lack of experience.

Patient concerns: A 24-year-old woman presented with erythema, crusted papules, pain and swelling on the nose after receiving the injection of hyaluronic acid. A swab of the discharge fluid was obtained for bacterial and viral culture, showing positive for herpes simplex virus.

Diagnosis: The patient was diagnosed as herpes reactivation after the injection of hyaluronic acid.

Interventions: The patient underwent antiviral therapy with acyclovir 400 mg, three times daily for seven days.

Outcomes: After a week of antiviral treatment, the clinical signs improved.

Conclusion: Herpes reactivation after the injection of hyaluronic acid is quite rare but needed sufficient attention of cosmetic practitioners to make the proper diagnosis, prevention and treatment.


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