Human Papillomavirus Infection in genital Women in four regions of Senegal

INTRODUCTION: Cervical cancer is the most frequent cancer among women in Senegal. However, there are few data concerning the HPV types inducing neoplasia and cervical cancers and their prevalence, in the general population of Senegal AIMS: The aim of this study is to determine the prevalence of HPV infection in Senegalese women aged from 18 years and older. MATERIALS AND METHODS: A study was performed on 498 cervix samples collected from healthy women aged 18 and older in Dakar. 438 other samples were collected from three other regions, Thiès, Saint Louis and Louga. The samples were screened for 21 HPV genotypes using an HPV type-specific E7 PCR bead-based multiplex genotyping assay (TS-MPG) which is a laboratory-developed method for the detection of HPV. RESULTS: The prevalence for pHR/HR