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Journal of Clinical Microbiology and Infectious Diseases

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The Genetic Base for Drug Addiction

Author(s): Srwsh N. qadr

Objective: There are many evidences about relationship between eating behavior and drug addiction. A number of susceptibility loci that point to shared higher order genetic pathways underling addiction were found in genetic studies. This study assumed that a genome-wide association study [GWAS] of food addiction would produce important enrichment in genes and pathways related to addiction. Methods: This study done among 314 women of European ancestry, by using a GWAS of food addiction, which is determined by the modified Yale Food Addiction Scale [mYFAS]. Results for enrichment of single nucleotide polymorphisms [SNPs] [n 5 44], genes [n 5 238], and pathways [n 5 11] involved in drug addiction were tested.


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