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Journal of Microbiology and Biotechnology Reports

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Topical Ciclopirox – Recalling a Forgotten Ally in the Fight against Cutaneous Mycoses

Author(s): Sidharth Sonthalia

 The injudicious use of antifungals, unselective use of corticosteroids for direct relief, persistence of predisposing features like sweat retention, and uncontrolled diabetes, and developing resistance to antifungals across the globe have rendered the management of an erstwhile simple infection, the superficial cutaneous mycoses highly complicated and tricky. Ciclopirox (CPX) is an old yet efficacious, versatile, and safe topical antifungal of the hydroxypyridone family. Despite its numerous beneficial properties over majority of other topical antifungals, it is being under-utilized owing to aggressive focus and tactics of the pharmaceutical industry on promoting ‘newer azoles’.


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