The occurrence of tattoos –heavy metal's dye with associated adverse skin reaction markedly increased in the last two decades. A 29 years old female was suffering from persistent ulcerative crater lesion on her upper left hand in middle area of orange to red decorative tattoos near the shoulder joint due to underwent to Magnetic Resonance Imaging (MRI) after car accident. Complete healing of ulcerative lesion was achieved by application treatment protocol combined of antibiotic, cortisone and topical AQUACEL Ag foam/surgical (convaTec) wound dressing. Tattoos heavy metaldye may induce skin reaction starting from simple inflammatory reaction to end up with breakdown of persistent skin reaction.

Alongside regulation, standardization is an important element for implementation of high quality requirements for tattoo inks and tattoo. A tattoo is the result of the deposition of exogenous pigment into the skin. This may be purposeful or accidental. Accidental tattoos may occur after abrasion injuries introducing asphalt, graphite, or carbon into the injured skin. Rarely, medically induced tattoos have developed after the use of ferrous sub sulfate solution (Monsel's solution) for coagulation purposes. While traumatic tattoos are not rare, decorative tattoos are more common. Tattooing has been practiced for thousands of years for purposes of identification, group affiliation and protection, and artistic expression. Tattooing is getting increasingly popular among the young. However, not everyone is suited to getting tattooed. Indeed, it is not rare for patients with a chronic skin disease or another systemic condition to be eager to get a tattoo.