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Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic

Publications

  • Reviews   
    Hypoxia and the heart of poikilotherms
    Author(s): Bohuslav Ostadal*

    Hypoxic states originate as a result of an insufficient amount of oxygen supplied to the cardiac cell and the amount actually required by the cell. The dominant factor affecting the supply of oxygen to cardiac structures is governed by the type and overall capacity of the cardiac blood supply. Whereas the heart of adult homeotherms consists entirely of compact musculature with coronary blood supply, the cardiac musculature of poikilothermic animals consists either entirely of the avascular spongious type, supplied by diffusion from the ventricular cavity, or its spongious musculature is covered by an outer compact layer supplied from coronary arteries. As a whole (ie, without distinction between the compact and spongious layer), the adult poikilothermic heart is significantly more tolerant to oxygen deprivation compared with the homeothermic heart, probably because of higher anaerobic.. Read More»
    DOI: 10.4172/2368-0512.1000008