Uniosun Teaching Hospital, Osogbo, Osun State, Nigeria

Publications

• Research Article   
  EFFECT OF CHRONIC INGESTION OF Allium cepa (WHITE ONION BULB) ON PLATELET AGGREGATION IN AN AGED FEMALE WISTAR RAT
  Author(s): Bolarinwa Kabir Adekunle*
  
  Aging is associated with an increased incidence of cardiovascular disease and thrombosis. Several lines of evidence support that platelets from older subjects differ in their function and structure, making platelets more prone to activation and less sensitive to inhibition. These age-related changes could lead to platelet hyperactivity and to the development of a prothrombotic state in advanced age. The effect of aging on platelet may be related to reduce hematopoietic stem cell reverse in aging individuals. As such, discovery of natural products or supplements that will provide anti-thrombotic effect on the platelets of aged female wistar rat is sorely needed. The aim of this study is to investigate the effect of chronic ingestion of Allium cepa on platelet aggregation and some coagulation parameters in aged female wistar rats. A total of 30 aged female wistar rats were used in this .. Read More»
  DOI: 10.37532/puljds.2022.5(6).1-9

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