Commentary
Sporothrix brasiliensis infection of domestic cats in the Brazilian sporotrichosis hyperendemic region
Author(s): Edward Wagner*
Microbial interactions have the potential to influence a patient’s diagnosis, prognosis, and therapy. Sporotrichosis, caused by Sporothrix brasiliensis, is a hyperendemic neglected zoonosis in Brazil. In a sporotrichosis hyperendemic area of Brazil, four pairs of clinical isolates of Sporothrix were obtained from four ill cats (CIM01-CIM04, two isolates per animal), highlighting the potential of coinfection. In mycological cultivation, each of the pair’s isolates had different pigmentation, and they were labelled “Light” or “Dark” for low and high pigmentation, respectively. By ELISA and FACS quantification, dark isolates responded strongly with monoclonal antibodies to melanin (p 0.05), and immunofluorescence revealed a ring pattern with certain sections having stronger punctuated staining at the cell wall. Light isolates, on the other hand, respon.. Read More»
DOI:
10.37532/puljcmid.2022.5(2).15
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