Research Article
Brain metastasis from ovarian cancer
Author(s): Tressie Herrmann, Judith Passildas Jahanmohan*, Ioana Molnar, Marie-Ange Mouret-Reynier and Xavier Durando
OBJECTIVE: Brain metastasis from ovarian cancer is a rare phenomenon and only a few studies have focused on it. The present trial aimed to evaluate the predictive factors involved in its development, and the outcomes for women with this kind of evolution, based on exploration of real-life data.
METHODS: This was a single-center retrospective study conducted on data of fifty women with brain metastasis from ovarian cancer treated from 2001 to 2021.
RESULTS: The presence of a high-grade serous carcinoma was a significant factor for the development of secondary brain lesions. Older age at metastatic diagnosis and platinum sensitivity were good predictive factors. Surgery of the primary lesion was also a significant factor for good prognosis. In multivariate analysis age at brain metastasis, more than 2 lesions and sensitivity to platinum salts were three significant p.. Read More»
DOI:
10.37532/pulcmr-2023.6(2).68-71