Predictors of thromboembolic and bleeding complications in patients with non-valvular atrial fibrillation and atrial flutter using vitamin K antagonists or non-vitamin K antagonist oral anticoagulants A cross sectional study
Author(s): Natasa Jankovic*, Jovana Kuzmanovic Pficer, Biljana Pantic, Dragan Simic MD and Vedrana Pavlovic
Background: Most common complications that could occur due to inadequate anticoagulant therapy are different types of bleeding or thromboembolic events. Objectives: The aim of this study was to identify differences between patients using a different anticoagulant therapy and the occurrence of complications and their frequency. The second aim was to determine the predictors that may lead to these complications using the regression model. Methods and Results: We conducted a cross-sectional study. In total, 1401 AF/AFL patients were identified with prescriptions to either VKA or NOAC. Duration of follow-up was 22.5 months. The results showed no significant differences between NOAC and VKA users for ischaemic stroke or systemic embolism. On the other hand, in the VKA group, there were two times more fatal outcomes than.. Read More»
DOI: 10.37532/pulcj.22.6(4). 51-57.