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The aging phenomenon in men is the result of a process that is different from that in women; however, the clinical manifestations may be similar. The term ‘andropause’ is used to define partial testosterone deficiency in the aging male. The symptoms of andropause are numerous, and are related to decreased multihormonal concentration and efficacy. To date, testosterone deficiency seems to be a significant factor in the male aging process. The present paper reviews screening, diagnosis and the symptoms of andropause.