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Anatomical anomalies represent deviations from the typical anatomical structure of the human body. These variations can be congenital or acquired and may range from benign to clinically significant. This article provides an in-depth review of the classification, causes, diagnostic approaches, and clinical implications of anatomical anomalies. Emphasis is placed on the importance of recognizing these variations in clinical practice, especially in surgery, radiology, and pathology. Through the integration of case studies and current literature, this research aims to enhance understanding and awareness of anatomical anomalies among medical professionals and researchers.