Clinical Report of Stem Cell Therapy in Iranian Neurologic Patients

 Accordingly, in the present review, the authors are trying to discuss stem cell-based biotechnologies as promising therapeutic options for neurological disorders secondary to COVID-19 infection through reviewing neurological manifestations of COVID-19 and current stem cell-based biotechnologies for neurological disorders. Stem Cell Therapy is a chance to treat several non-treatable diseases like Neurologic diseases. There are many ambiguous questions in this regard that need to be examined in clinical trials in different diseases and different stem cells. 1-Is the use of pure and cultured mesenchymal cells more effective or fresh mesenchymal cells with progenitor cells (Stromal Vascular Fraction)?  2-Which kind of source is suitable for which kind of disease, Allogeneic or Autologous? 3- Is Adipose tissue-derived cell more effective than hematopoietic ones, in myopathic patients? 4- How long does the stem cell therapy benefit? Is it dependent on cell dose or cell type? And the unknown more and more questions need to know the exact reports of exact clinical trials.In this panel, we will review Iranian stem cell therapy clinical trials in neurological diseases like Cerebrl Palsy, Friedrich Ataxia, CADASIL, Multiple Sclerosis.