Sign up for email alert when new content gets added: Sign up
In the practice of forensic genetic examination, there are cases when the biological trace on physical evidence is left by an unknown male person. In such cases, along with the definition of the genotype of an unknown person, studies on the Y-chromosome are performed on the STR loci of nuclear DNA. In most cases, these studies lead to the successful disclosure of the crime. But sometimes, despite the large number of samples examined, the suspect cannot be identified. In most such cases, DNA samples of individuals living in the same area are examined. To narrow the circle of suspects, calculate the lifetime of a common ancestor, through which it is possible to obtain information about related affinity and narrow the circle of suspects. Later, these results will be used to determine the relationship on the paternal line, where a reliable knowledge on mutation properties is necessary for correct data interpretation. When determining the degree of solution on the paternal line, if discrepancies between the child’s father and other paternal relatives are not taken into account, population-specific mutation rates should be used to determine if this is a mutation or a true exception. Therefore in this study, we aim to determine the mutation rates of 17 Y-STR loci in Uzbekistan.
Journal of Clinical Genetics and Genomics received 18 citations as per Google Scholar report