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Journal of Clinical Genetics and Genomics

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Exploring the correlation between body constitution of an individual as per Ayurveda and gut microbiome in Healthy,multi ethnic urban population in Bangalore, India

Author(s): Shalini TV

 Prakriti (body – mind constitution of an individual) is a traditional, altered and interesting the comprehension of which is fundamental for the customized medication depicted in Ayurveda, Indian System of Medicine. In light of the Doshas( utilitarian, bio humoral unit in the body) people are classified into three significant prakriti-Vata, Pitta and Kapha. The human gut miniature biome has a lot of exceptionally assorted and metabolically dynamic microorganisms, mostly overwhelmed by the microscopic organisms, which are known to impact the physiology of a person. Scarcely any explores have indicated the relationship between's the prakriti and the biochemical boundaries. In this investigation, an endeavor was made to investigate any connection between's the prakriti (aggregate of a person) with the Genetic cosmetics of the gut miniature biome in solid people.

Materials and strategies:

270 multi ethnic, sound volunteers of both the sex with the age bunch between 18 to 40 years, with no set of experiences of anti-microbials in most recent a half year were enrolled into three gatherings of Vata, Pitta and Kapha. The Prakriti of the individual was resolved utilizing Ayusoft, a product planned by CDAC, Pune, India. The volunteers were exposed to beginning screening for the appraisal of their tallness, weight, Body Mass Index, Vital signs and Blood examinations to guarantee they are solid. The stool and salivation test of the enrolled volunteers were gathered according to the standard working system created and the bacterial DNA was confined utilizing Qiagen packs. The extricated DNA was exposed to 16s rRNA sequencing utilizing the Illumina units. The sequencing libraries focusing on the variable V3 and V4 districts of the 16s rRNA quality. Matched sequencing was done on MiSeq framework and information were examined utilizing the CLC Genomics workbench 11. Ayurveda is one of the most seasoned wellbeing studies of the world. It depends on the ideas of tridosha and prakriti as the focal methods of reasoning. The essential point of Ayurveda is upkeep of wellbeing and improvement of problems in unhealthy individuals. Modernized practices got from Ayurveda conventions are on comparable lines with current clinical practices (Sen and Chakraborty 2017). The current investigation is the principal report clarifying the point by point connection of dominating Ayurvedic prakrities (vata, pitta and kapha) with the different human microbiomes (gut, oral and skin) of the people for unwinding the microbiome and prakriti affiliations. Ayurveda depicts three crucial elements that administer our inward and external conditions, viz. development, change and structure, and are referred to in Sanskrit as vata, pitta and kapha, separately (Pal 1991). These essential powers are liable for the attributes of our psyche and body. Furthermore, every one of us has a one of a kind extent of these three powers that shapes our inclination.


The 16s rRNA sequencing of V3 and V4 area demonstrated assorted example in both the oral and stool microbial DNA. The examination didn't uncover a particular example of bacterial verdure among the prakriti. All the p-values were more than the powerful alpha qualities for all OTUs in both buccal pit and feces tests. Subsequently, there was no noticed huge improvement of any OTU in the patient examples from either buccal depression or feces tests.


In solid volunteers of multi identity, because of the impact of the different variables, relationship betwwen the prakriti and the gut microbiome was not seen.

Google Scholar citation report
Citations : 24

Journal of Clinical Genetics and Genomics received 24 citations as per Google Scholar report