Iron deficiency anemia treatment in CKD and end-stage kidney disease

People with chronic renal illness frequently have iron deficiency, which is a primary factor in the emergence of anemia. For patients with chronic renal disease who have an iron deficit, both oral and injectable iron treatments are available. The most common factors influencing the decision of which agent to use are the therapeutic goals, acceptability, practicality, and response to previous therapy. Iron deficiency anemia must be treated with intravenous iron formulations, especially in patients requiring kidney replacement therapy, due to decreased iron absorption in the gastrointestinal system and a high incidence of gastrointestinal side effects. Newer oral medications might help to get around these restrictions and treat iron deficiency in those who don't need renal replacement therapy. According to this research, patients with chronic renal disease who need kidney replacement therapy may benefit from more aggressive iron replacement in terms of managing anemia and important clinical outcomes including cardiovascular disease and survival.