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Journal of Phlebology and Lymphology

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Management of no-reflow: Still an unsolved problem?

Author(s): Alessandro Mandurino-Mirizzi*, Marcello Spolverini, Andrea Attanasio and Gabriele Crimi

No-reflow represents an important limitation of percutaneous coronary intervention in patients with ST-elevation myocardial infarction. Importantly, no-reflow is associated with an increased risk of major adverse cardiac events. In this review, we discuss the pharmacological and nonpharmacological interventions proposed for the prevention and treatment of no-reflow, highlighting the new updates and evidences on efficacy of these approaches.


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