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Methylene blue anaphylaxis under anaesthesia, during sentinel lymph node mapping in a patient undergoing bilateral mastectomy

Author(s): Melissa Sharpless* and Michael Williams

Methylene blue is a widely used dye for sentinel lymph node mapping for solid tumours especially breast cancer. Anaphylaxis is a life threatening reaction that can occur during Anaesthesia. Methylene blue has been reported to be the safest dye, indeed a recent systematic review and metaanalysis reported no cases of anaphylactic reactions. We report a case of a 37-yr-old female who experienced an anaphylactic reaction to methylene blue resulting in Intensive Care Admission.


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