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Journal of Kidney Treatment and Diagnosis

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MicroRNAs in diabetic kidney disease

Author(s): Fiona Hardman

Diabetic kidney diseases is one of the diabetic microvascular complications.

Type 1 and type 2 diabetes are particular in etiology and pathogenesis.
Notwithstanding unique morphological changes of renal injury in type
1 and type 2 diabetic patients, type 1 and type 2 diabetic patients have
comparative dangers of renal injury in ailing kidney. The qualities of diabetic renal injury incorporate the destruction of podocyte foot measures, slow mesangial cell multiplication and hypertrophy, unreasonable collection of extracellular framework proteins, mesangial extension, and thickening of the glomerular storm cellar layer. These occasions in the end lead to nodular glomerulosclerosis Kimmelstiel-Wilson injuries. Comparative changes happen in the tubulointerstitial, like cylindrical hypertrophy, thickening of the rounded storm cellar layer, and interstitial fibrosis

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