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International Journal of HIV and AIDS Research

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Molecular epidemiology of human immunodeficiency virus type 1 and therapeutic monitoring of patients treated in Kinshasa/Democratic Republic of the Congo

Author(s): Erick Ntambwe Kamangu, Roger Di-Mosi Wumba, Hippolyte Nani-Tuma Situakibanza, Prosper tshiloba Lukusa, Liévin kalala Kapend, Georges lelo Mvumbi, Marie-pierre Hayette, Richard lunganza Kalala

CONTEXT: The introduction of Antiretroviral Drugs (ARVs) has reduced morbidity and mortality associated with the Human Immunodeficiency Virus (HIV) infection. But also at the other hand, the massive use of these molecules created the emergence of mutant strains resistant to the treatment.

OBJECTIVE: The objective set for this study was to determine the different variants of HIV-1 group M circulating in Kinshasa, the prevalence of mutations associated with resistance to antiretroviral treatment and their involvement in therapeutic monitoring of infected patients followed in different centers.