Understanding lymphedema: pathophysiology and implications for clinical management

Lymphedema is a chronic and progressive condition characterized by abnormal accumulation of lymphatic fluid, leading to swelling and tissue changes. The pathophysiology of lymphedema involves
disruptions in the lymphatic system, including impaired lymphatic drainage and inflammation. This article provides an in-depth exploration of the pathophysiological mechanisms underlying lymphedema and discusses their relevance for clinical management. Understanding the intricate molecular and physiological processes involved in lymphedema is crucial for the development of effective therapeutic strategies.