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Hospital and Health Care, Glendale, Arizona, USA


  • Original Article   
    Clinical outcomes of ondansetron administration with elective cesarean section
    Author(s): Lee Ranalli, DNP, CRNA* and Barbara Dvorchak, BSN, CRNA

    Background: Intraoperative vital sign variability such as hypotension and bradycardia continue to remain a concern for patients undergoing cesarean delivery under spinal anesthesia. Recent literature has suggested that administering a 5-hydroxytryptamine3 antagonist such as ondansetron prior to spinal anesthesia for cesarean delivery can mitigate intraoperative vital sign variability and reduce vasopressor utilization. Purpose and objectives: The purpose of this project was to examine the optimal perioperative timing of ondansetron administration and associated maternal clinical outcomes with elective cesarean delivery. The main objectives were to determine if intraoperative hemodynamic variables and vasopressor administration significantly differed regarding ondansetron timing. Method: A retrospective medical record r.. Read More»
    DOI: 10.14303/2632-251X.100003

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