Mini Review
Exploring Structural Variations: Implications for Phenotypic Diversity, Disease Susceptibility, and Precision Medicine
Author(s): Natalisa Hvizdosova*
Structural variations refer to genomic alterations that involve changes in the
DNA sequence, such as insertions, deletions, inversions, duplications, and
translocations. These variations can have significant implications for human
health and disease. This mini review aims to provide an overview of structural
variations, highlighting their types, prevalence, mechanisms of formation, and
impact on phenotypic diversity and disease susceptibility. The review begins
by defining structural variations and their classification based on size and
genomic location. It then explores the various mechanisms that contribute
to the formation of these variations, including errors in DNA replication,
recombination events, and mobile genetic elements. The review further
discusses the role of structural variations in evolutionary processes and their
association with genet.. Read More»
DOI:
10.37532/1308-4038.16(5).268
+447723598358
