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Academy of science, Liaoning University, Shenyang, China

Publications

  • Original Article   
    Preparation and study of the physicochemical properties of psoralen-doxorubicin nanostructured lipid carriers
    Author(s): Tiange Cai, Chuling Du, Yinghong Huang, Xi Xia and Yu Cai*

    The purpose of the present study was to prepare psoralen-doxorubicin nanostructured lipid carriers (PSO-DOX-NLC) with better physicochemical properties for further study on its multidrug resistance reversal activity on leukemia cells. PSO-DOX-NLC was synthesized by emulsion evaporation and solidification at a low temperature. PSO-DOX-NLC morphology and particle size were examined using transmission electron microscopy, and Zeta potential was determined using photon correlation spectroscopy; encapsulation efficiency was also investigated. The results showed that PSO-DOX-NLC possessed a rounded structure, with a mean (± SD) particle size of 128.7±1.8 nm, a polydispersity index of 0.22±0.01, a Zeta potential of 20.17±0.31 mV, a psoralen encapsulation rate of 76.56% and a doxorubicin encapsulation rate of 89.48%. Thus, PSO-DOX-NLC p.. Read More»
    DOI: 10.4172/2529-797X.1000009

 
Google Scholar citation report
Citations : 67

Current Research: Integrative Medicine received 67 citations as per Google Scholar report

Current Research: Integrative Medicine peer review process verified at publons
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