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Clinical Pharmacology and Toxicology Research

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The impact of Lambda cyhalothrin insecticide on the parameters and chemical metabolites in the kidneys of Wistar rats

2nd International Conference on TOXICOLOGY AND CLINICAL TOXICOLOGY

November 11-12, 2019 | London, UK

Guefaifia Yahia

University of Tebessa, Algeria

ScientificTracks Abstracts: Clin Pharmacol Toxicol Res

Abstract :

Lambda cyhalothrin is a synthetic pyrethroid insecticide type II, with increasing agricultural uses. This active substance consists of two of the four enantiomeric forms of cyhalothrin. This study was carried out on a group of rats (18 rats) treated with LCT (05 mg / kg / day), group C (06 rats) treated with LCT (10 mg / kg / day) orally for 90 days This work is for the evaluation of the potential toxicity of LCT on the kidneys of rats and the variation of certain biochemical parameters and metabolites. The results obtained after administration of LCT show that it caused an increase in urea and creatinine also a disturbance of the main macromolecules namely proteins, lipids in treated rats with this two doses compared to controls. All of these variations are signs of the toxicity of this insecticide to the kidneys of Wistar rats.

Biography :

Guefaifia Yahia completed his bachelor diploma in animal biology and physiology and his master diploma in animal Ecophysiology from Tebessa University. He is now working as a pharmacist.

E-mail: yahya.out12@gmail.com

 
Google Scholar citation report
Citations : 27

Clinical Pharmacology and Toxicology Research received 27 citations as per Google Scholar report

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