A dicyanoisophorone-based highly sensitive and selective nearinfrared fluorescent probe for sensing thiophenol in water samples and living cells

Alzheimer’s disease (AD), as the most common progressive neurodegenerative disorder, is pathologically characterized by deposition of extracellular plaque composed of amyloid-β peptide (Aβ). Therefore, the development of reliable assays for Aβ (both monomers and oligomers) are important for the early differential diagnosis of dementia, predicting the progression of AD, as well as monitoring the effectiveness of novel anti-Aβ drugs for AD. Recently, our group has constructed several analytical assays for sensing Aβ (both monomers and oligomers): by using