44 2033180199
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Journal of Kidney Treatment and Diagnosis

Sign up for email alert when new content gets added: Sign up

Adaptive nephrology

Author(s): Hanna Koch* and Paul Hohenlohe

Evolutionary medicine, a new field that broadens study boundaries, has evolved in the last 20 years. Progressive kidney disease follows nephron loss, hyperfiltration, and inadequate healing, a process known as "maladaptive." Evolutionary adaptation, in contrast to physiological (homeostatic) adaptation, is the result of reproductive success, which represents natural selection. Environmental mismatch or evolutionary trade-offs can lead to evolutionary reasons for physiologically maladaptive responses. A fragile, energy-hungry renal tubule and a hypoxic, hyperosmolar microenvironment were produced as a result of evolutionary adaption to a terrestrial environment. Natural selection promotes a successful energy investment strategy: through the reproductive years, energy is committed to maintaining nephron integrity, but after age 40, this decreases due to senescence.

Full-Text | PDF

Recommended Conferences

20th World Congress on Clinical Pediatrics

Edinburgh, Scotland

5th World Congress on Pathology and Clinical Practice

Amsterdam, Netherlands
Google Scholar citation report
Citations : 11

Journal of Kidney Treatment and Diagnosis received 11 citations as per Google Scholar report

Global Tech Summit Top