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Hichem Kolsi, Wael Jawadi, Ali Chaabouni, Med Fki, Koytheir Walha and Abdelhamid Karoui
Habib Bourguiba University Hospital, Tunisia
ScientificTracks Abstracts: Surg Case Rep
Objective: The objective of this study was to assess whether the central venous-to-arterial carbon dioxide partial-pressure difference (ΔPCO2) and the ratio of the ΔPCO2 to the arterial-venous difference in oxygen content (ΔPCO2/Ca-vO2) predict postoperative complications (PC) after cardiac surgery. Methods: Prospective, observational, noninterventional study, about 60 patients undergoing cardiac surgery with cardiopulmonary bypass. The primary endpoint was the occurrence of PC. Data were first analyzed in two groups based on the occurrence of PC. Then, receiver operating characteristic curves of the ΔPCO2 and the ΔPCO2/Ca-vO2 ratio were analyzed for the prediction of PC. Measurements and Main Results: Among the study participants, 22 (36.7%) experienced PC. The death rate was 18.3%. The present study found that the ΔPCO2 and the ΔPCO2/Ca-vO2 ratio predicted the occurrence of PC with areas under the curve of 0.702 and 0.666, respectively. The best thresholds of these markers were 8.3 mmHg for the ΔPCO2 and 2.16 mmHg/mL for the ΔPCO2/Ca-vO2 ratio. A significant difference was found for these indicators between the groups with and without PC. The ΔPCO2 and the ΔPCO2/Ca-vO2 ratio were significantly correlated to EuroSCORE II, duration of aortic clamping, majority of prognostic scores the first two days postoperatively and the lactate level. The ΔPCO2/Ca-vO2 ratio is predictive of hyperlactatemia >2 mmol/L, with an area under the curve of 0.787. Conclusion: The ΔPCO2 and the ΔPCO2/Ca-vO2 ratio predict the occurrence of complications in cardiac surgery. This was in occurrence with physiological knowlage(1) and other author’s results(2). But, our results are not consistent with other studies that not found any correlation between ΔPCO2 and the ΔPCO2/Ca-vO2 ratio and prognostic indices(3,4). Recent Publications 1. Acute angle-closure glaucoma after total knee replacement surgery: case report and literature revue 2. The Ability of Carbon Dioxide–Derived Indices to Predict Adverse Outcome After Cardiac Surgery 3. Intra-articular analgesia: comparing 50mg and 100mg of tramadol with morphine for analgesia after arthroscopic knee surgery
He is currently working at habib bourguiba university hospital, Tunisia.
