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Journal of Immune Disorders & Therapy

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Genetic characterization of s1 domain of porcine epidemic diarrhea viruses spike proteins isolated in Korea

Author(s): Hee-Chun Chung, Van Giap Nguyen, Hyoung-Joon Moon*, Bo-Kyu Kang, Sung-Jae Kim, Hye-Kwon Kim, Seong-Jun Park and Bong Kyun Park*

We analyzed spike gene of the three PEDV isolated during 2014 to 2015 in our lab (Strain J3142, BM1, and BM3). In phylogenetic study, 3 strains belong to gene subgroup G2a, and between three strains, BM1 and BM3 have higher similarity with the strains from North America. On the other hand, J3142 was more closely related to China strain and has some variation in the S1 region (1,938- 2,077nt) compared to BM strains. Especially from the data, analyzing N-terminal domain and C-terminal domain, N-terminal domain showed little homology to strains from USA and China.

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Citations : 3

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