HOME
Return to Table of Contents
83 ADMINISTRATION OF METOCLOPROMIDE BEFORE CAPSULE ENTEROSCOPY INCREASES THE PERCENTAGE OF COMPLETE SMALL BOWEL EXAMINATIONS WITHOUT DECREASING THE DIAGNOSTIC YIELD RK Ghanta, M Rastogi, R Rastogi, RK Vemuru, BACKGROUND AND AIM: Incomplete clearance of M2A capsule has been one of the problems in examination of the small bowel. Increasing the motility of gastrointestinal tract by administration of metoclopropamide was reported to increase clearance of the capsule and decrease the transit time. Because the number of images being taken per unit time remains a constant, we wanted to examine whether increasing the speed of passage of the capsule would result in decreasing the diagnostic accuracy of the examination.
Permian Gastroenterology associates and Texas Tech Health Sciences Center at Odessa, Texas, USA
METHODS: A total of 194 patients that have completed capsule enteroscopy examination in a private practice setting were analyzed. Sixty-three of these 194 patients had received 10 mg of liquid metoclopropamide 30 min before initiation of capsule enteroscopy. Differences in gastric emptying time, small bowel transit time, percentage of complete small bowel examinations, as well as the overall diagnostic yield was measured between the two groups. Patients with incomplete clearing of the small bowel secondary to obstructive lesions were excluded from the calculations for small bowel transit time and percentage of complete small bowel examinations.
RESULTS: No significant decrease in gastric emptying time was observed with administration of metoclopropamide (41 min vs 35 min). No appreciable difference in small bowel transit time was noted with administration of metoclopropamide (208.4 min vs 192.6 min). In the absence of obstructive lesions complete clearance of small bowel was noted to be higher among patients who had received metoclopropamide (98% [63/64] vs 89% [117/131]. However, no significant differences in diagnostic yield was noted with administration of metoclopropamide (49.61 vs 51.56 with metoclopropamide)
CONCLUSION: Administration of metoclopromide 10 mg orally 30 min before CE will increase the likelihood of complete small bowel evaluation without affecting the overall diagnostic yield.